Daniel Radcliffe has made a "major donation" to The Trevor Project, a non-profit organization that operates the only nationwide, around-the-clock crisis and suicide prevention helpline for lesbian, gay, bisexual, transgender and questioning (LGBTQ) youth.
Bruce Glikas, FilmMagic
Continuing their long history of charitable and humanitarian donations, Brad Pitt and Angelina Jolie are donating $1 million along with Pitt's brother Doug to St. John's Hospital in Springfield, Missouri. The money will be used to build a cancer treatment center.
Kevin Winter, Getty Images
'Ugly Betty' star Vanessa Williams has teamed up with Dress for Success, which provides donated business attire to disadvantaged women and helps them succeed in the workplace.
ABC
'Grey's Anatomy' star Patrick Dempsey is taking his love of car racing and using it for good, as 'McDreamy' auctions a weekend with himself off to the highest bidder. Proceeds will go to benefit a children's burn hospital in Denver.
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Mia Farrow completed a 12 day hunger strike to raise awareness for the plight of starving refugees in the Sudan. She had set out to fast for three weeks, but gave up nine days shy under the advice of her doctors.
Salvatore Di Nolfi, Keystone / AP
Actor Hugh Jackman announced on Ryan Seacrest's radio show that he has split a $100,000 donation between Charity: Water and Operation of Hope. The donation is part of a "contest" Jackman held via his official Twitter profile.
Sean Gallup, Getty Images
'Top Chef' judge Tom Colicchio is heavily involved with the Children of Bellevue program, which assists and educates kids treated in the New York City hospital. Sixteen years ago, the organization assisted his family when his son Dante was born prematurely. He's hoping his efforts will provide continued support to families in need of medical care for children.
Stephen Lovekin, Getty Images
For the past 5 years, 'One Tree Hill' star James Lafferty has organized a charity basketball game, benefiting organizations like St. Jude Children's Research Hospital. He's forced to cancel this year, due to intrusive and threatening behavior by fans.
Getty Images
Oprah Winfrey has invested $40 million in her Academy for Girls in South Africa and raised over $58.3 million for various non-profits through her Oprah's Angel Network. Plus, she's given cars, hams, toasters, etc. to underprivileged audience members on her show.
Denis Farrell, AP
She gives no mercy on the bench, but famously nasty-on-TV Judge Judy Sheindlin is much more charitable in real life. She supports a mentoring program called Her Honor, which pairs high school juniors and students with dynamic female leaders.
Brad Barket, Getty Images
Comedian Drew Carey is using Twitter to give back to cancer research. On Friday, Drew Olanoff, a Twitter user who encourages a positive approach to living with cancer, invited bids of more than $10,000 for his @drew account to raise money for cancer support. 
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Tuesday 06 October
By Icarus
Re: the Brad and Angelina item, please slap your copy editor. The way your copy is phrased makes it sound like Brad and Angelina are giving a hospital $1 million AND Brad's brother Doug. The proper way to say this is that Angelina, Brad and Brad's brother Doug are donating $1 million. If you're going to be in the communication business, then communicate.
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