In what has already been a season of big guests, talk show mogul Oprah Winfrey will soon sit down with film critic and close personal friend Roger Ebert, Boston.com is reporting.

The interview -- which airs Tuesday -- will be especially notable, as Ebert's recent bout with thyroid cancer has rendered him speechless. To accommodate, Ebert will use text-to-speech computer technology to field Oprah's questions, according to the report. His wife, Chaz, will also make an appearance.