It's been 20 years since her role as a 'Pretty Woman,' but Julia Roberts is looking prettier than ever. For the fourth time, PEOPLE magazine has given her top honors in their annual Most Beautiful issue. "She's never looked more beautiful," said Ryan Murphy, director of her newest film, 'Eat, Pray, Love.' "She is so happy and fulfilled and it shows."

Roberts, 42, took on another flattering title back in January when she signed her first beauty contract to become Lancome's global ambassador. "It's fun to find myself with this type of new career at my advanced age," she said of her new position. After the jump, see what other celebs (like Justin Bieber) had to say about making the list!

Julia Roberts