Madonna in Interview Magazine

If there's something Madonna has certainly never lacked, it's ambition. If there's two things ... the second trait would be bravado -- and both are flaunted in a new interview and photo shoot the Material Girl gives to Interview Magazine for their May issue. During Madonna's chat (conducted by director Gus Van Sant), she talks about how she balances work and her kids, her trips to Malawi and why Sean Penn has "a fire under his ass." Saucy! Quotes and pics after the jump!