The shocking news that David Arquette and Courteney Cox have separated after 11 years of marriage took everyone by surprise this week, except Courteney's longtime pal Jennifer Aniston.

"Jen has known for some time that the couple was in trouble but hoped and prayed they would be able to work it out," a friend of the actress tells me. "No one knows how painful divorce is more than Jen and she hopes they don't rush into it without exhausting every possibility to stay together."