'Saturday Night Live' is in hot water this week thanks to a controversial skit it aired during last weekend's show.

According to E! News, the Gay & Lesbian Alliance Against Defamation (GLAAD) is up in arms over a parodied commerical for a fake product called Once Daily Estro-Maxx, a pill designed to "give you all the sex-changing hormones you need."

Male 'SNL' cast members, including Bill Hader, are pictured as transgender women talking about their bodies and hormone levels.

"The piece was a mock commercial for estrogen replacement therapy and featured men with facial hair wearing dresses, meant to represent transgender women," GLAAD said in a statement. "This segment cannot be defended as 'just a joke' because there was no 'joke' to speak of."