Zach Galifianakis Bill Maher Heroin VideoZach Galifianakis is sure upping the ante when it comes to his on-air drug use. Forget marijuana, Galifianakis is clamoring to join the big leaguers who partake in the high-life.

In October 2010, Galifianakis set the Internet on fire after his appearance on Bill Maher's 'Real Time.' Maher threw up a still shot of Galifianakis smoking a joint on the show and announced that the clip of that appearance "got over 2 million hits on YouTube."

In an effort to generate even more buzz, Maher pulled out a tray with all the paraphernalia to shoot Galifianakis up with heroin.