Eric Dane and Rebecca Gayheart already have a toddler at home, and now the actors are going to be parents for a second time.

The couple is expecting their second child, a source confirmed to PEOPLE.

The 'Grey's Anatomy' actor and Gayheart, who were married in 2004, welcomed their first daughter, Billie Beatrice, in March 2010.

"I don't know if there's any change more significant that a human being can make than that of a woman becoming a mother. There's no change more dramatic," Dane gushed to PEOPLE about his wife earlier this spring.

"You know, I'm a hundred times more attracted to her now and I love her exponentially more than I did before. It's just great to see her be a mother," he said.